Since its initial development in the 1980s, the technology of Lateral Flow Immunoassay has gained wide acceptance (Wong and Tse, 2008).
This technology is based on the principle of antigen-antibody reaction. It is characterized by labeling colored particles on the detector protein. Depending on the assay, either antigen or antibodies are immobilized on a nitrocellulose membrane in a cartridge device.
This technology is in use for a wide range of tests for clinical, veterinary, and industrial applications. The most well-known example is a home pregnancy test. The lateral flow immunoassay devices are compact and portable (see above figure). Most of them do not require external reagents for results. The addition of a liquid sample would initiate and complete the test. Results are quick and easy to interpret, usually without the help of an instrument.
Mirimedix has been developing test kits (MirichekTM series) for detecting viral pathogens (SARS-CoV-2, Japanese encephalitis virus, Zika virus, Dengue virus and HIV) and stress markers (Cortisol) using the above technology.